I use the serum in combination with the day / night cream for about 2 weeks. Now I have to say that I, to high-end products have almost all of drugstore offered range by far and could see no or almost no anti-wrinkle effect. I am in my mid 40 and have already boast some nasty wrinkles ;-) In the Age Perfect series I now first found a truly rejuvenating effect. Especially the unsightly wrinkles that could be seen when turning the head to the neck, are gone. The face looks interesting, fresh, clean and even. And even for relatively little money. I'm very satisfied. Finally a product that the skin's appearance, at least for me, clearly improved. However, I have also taken a lot lately, which took revenge with dry, pale skin and creases. My skin is drinking the serum away downright greedy. I can not with a clear conscience.