After 4 intervertebral disc operations at the cervical and lumbar spine ibuprofen 800 was very often necessary as a painkiller, in addition a tablet against the constant stomach cramps was also smashed. I do not know exactly what the MSM makes me in there, but replacing for 3 months 4x half a teaspoon of MSM (about 12-14g) the ibuprofen. Of course I go 2x a week still to Rehasport / physiotherapy. I feel already the pain slightly, but not as before, until the nausea, but the MSM seems to dampen the pain totally. However, I have exposed times of self-knowledge one day, but as the pain level was immediately very high. Initially I had too low, only 2x doses, but that was enough for me. 4x MSM and I feel relatively well. I can really recommend it for 3 months. Harald Ruppert