The PRS 350 I have now for about 4 weeks. A really great device. Text is very well presented, due to the slightly lower contrast compared to a gedrucken book, but you need a little more light. During the day or in sunlight I can read just fine with it, in bed at night with dim bedside lamp, it is a little more difficult than reading a book. But the reader is easier to hold and turn the page. To manage the books I use Calibre, accessed via tags (categories), authors and so on is good, the screen is sufficiently fast to allow good navigation. The battery life is very pleasant, I invite usually only on weekends (then still at least half full), the microUSB connector is practically (because only 1 charger for mobile and eReader needs). Most of my ebooks are PDFs. With the graphical representation of A4 documents I'm not so satisfied. But what do you expect from such a small screen. One is either the zoom or push. Sony has achieved relatively good, you can enlarge specific areas of the document and "freeze" also for the following pages to zoom. My feeling is A4 PDFs best seen with many graphics in landscape mode (upper / lower half, but then the writing is already pretty small). If only a few graphics contained or even plain text, reflow can be triggered by increasing or decreasing. Ie. The text is rewrapped as a TXT or EPUB file and can be displayed in different font sizes.
What is awesome in English Ebooks: Double-click on the unknown word translated appears. Great.
A disadvantage has the device yet: The stylus is Mies designed mine is broken in the inserted state (where the plastic clip is screwed into the metal sleeve, which is almost a breaking point). Replacement pins are not going to get on the open market, just a Sony partner and then for about 18 euros, puh.
A Lesetip I also have: The time there is very favorable than ePub subscription.