The HP X7500 is about 1.5 cm shorter and the scroll wheel is not quite as far forward as the reference mouse MS. Who has big hands and long fingers, consequently, might guess how much every centimeter counts when it comes to the ergonomic optimum, especially if one uses the mouse for many hours every day professionally.
The housing edges are quite sharp - to say: You can not cut or injure yourself, but the thumb and especially the little finger clearly feel the edges of the housing. But the sense probably depends on your hand size. Do not disturb the edges, my wife on the other hand significantly.
Unfortunately, you had the HP X7500 always be fitted with two AA batteries or rechargeable batteries. The reference of mouse MS, however can also be operated with only one battery. This is the MS-Mouse for a lighter and the other in the battery management more flexible, because I take when traveling with 2 batteries, but put only one. If the first battery suddenly empty, I still have a second ready as a reserve. I want to make in the HP X7500, I have to take four batteries so that the mouse suddenly lack of energy is not dead.
Other than that the HP X7500 is fully compatible with Windows 8.1, it has only one advantage over the reference mouse MS: It glides incredibly easy on the table tops in our house. The reference of mouse MS there was very picky.
Nevertheless, the HP X7500 is clearly the best Bluetooth mouse without a dongle, you (correctly: for a big right hand) for large hands may find on the market today.