From the history of discovery
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The bacterial strain has been known since the 1st World War. Among the soldiers who then in 1917 stationed in the Balkans, broke several times from a life-threatening diarrhea epidemic. Some comrades, however, remained healthy. In the intestinal flora of healthy surviving soldiers of Professor Nissle discovered the specific E. coli strain. (Source: Mutaflor.de -> History)
20 years later this bacterial strain (trade name Mutaflor) in the treatment of intestinal disorders of the Nazi dictator (AH) was set up by his personal physician. (Source: an N-TV broadcast)
My personal review
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My problem is that sounds pretty funny: bowel symptoms without disease. The doctors could not detect any disease and thus do not help. For years, various therapies (diet, Lactobacillus cocktails uv m). No Help. Until I met a GP who is a pharmacist studied simultaneously. He said treatment with E. Coli would be the only thing that could help in this case. Since that day, many years have passed. Today I know that this assumption was 100% correct.
I had started with E. Coli drop Symbioflor 2. This allows the dose increase slowly. After a few months I was able to upgrade to the high-dose Mutaflor capsules. The therapy has super helped me and caused enormous increase in quality of life. For that I am grateful to the doctor.
After long-term treatment with Mutaflor (2 J. Long, 1 capsule / day) I take refresher every year 50 capsules. Dosage: 1-2 capsules a day. More I will not for reasons of cost. Currently costs in online trade a 50 capsule pack about 36 euros, as of March 2015. Unfortunately, the health insurance pays nothing.
Conclusion
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Great help with intestinal problems. To date, noticed no side effects, only beginning in the familiarization phase. In spite of the long duration of treatment my warmest recommendation.