Yes !! the two microphones work with Guitar Hero and granny with all other games including a microphone is necessary.
They plug into a USB port, and actually in the words of one comment there "permetttant a USB hub to connect multiple microphones at the same time," 3 more to be precise. (I call it a multi-USB, like a multi-socket, lol)
Their quality is very good, and the capture of the voice is more than efficient.
This is a very good choice for all karaoke games.
(PS: in case, the microphones are not wireless, as I believed until I come out of the box looool.)