Since the birth of my first I only use these wipes (since April 2010) never had any problems with either the buttocks or elsewhere (hands and face), and recently I subscribed to Amazon and every two months I have receiving 12 and each time I receive them in advance so by buying at Amazon I earn much (money, same quality at the store, time and one less thing to think) that Amazon would sell the layers with the same ratio / quality / price.