I have this backpack now nevertheless times praise publicly. I wear my regular EOS 40D with a Tamron 17-50mm and a Canon EF 100mm Macro around (A further standard lens I would also accommodate) and am very satisfied with the wearing comfort. Quick access to the camera by the side compartment works very well! At that time was decisive for my decision on this backpack! There are also numerous more useful subjects. Memory Card, cleaning kit, charger, remote shutter, etc. all find their place. Only an attachment for a tripod is missing but that yes there separate solutions.
Now a great feature farther, although not intended. It's a notebook compartment exists, but that one can fill water bladder with a 3 liter Streamer, which is very useful when hiking! A slight bulge there, unfortunately at the back but due to the good padding I do not find that so bad!
All in all, top price-performance and high flexibility!