The "Kandel" as he is popularly known neuroscientist is a previously unbeaten book within the scope of the issues, as well as in the intelligibility with which they are presented. In so far a must for every neuroscientist. However, it is just like any book specializing in biology questionable as the half-life of knowledge imparted looks, as you have read in many textbooks already in publication in the reviews that the issue would no longer appropriate. In fact, you have to face due to the advanced age the question how relevant is what has been learned, however, it is impossible to find another area to cross on this.