I usually use no creams as possible (except in the winter months). I am neither excessively vain, nor do I believe the many promises of the advertising.
Using a serum I have yet gathered any experience. The fact is, I have applied the serum in the evening and was really amazed at the more routine morning look in the mirror. Not about to all the wrinkles had evaporated overnight, but I saw clearly much fresher and not so tired rumpled as usual in the morning from? Coincidence? Resounding success after just one application? I could not believe it really. Now I creamed diligently again and in the evening and the next morning the same result. Fresh as the young day, hardly eye bags. I was excited.
On Monday morning, I admit, saw the matter from quite a bit different. Not quite so fresh (the night was also shorter) as the last two days, but ok. Nor is it so that I now rejuvenate me from day to day. The result is more consistent, but so far I'm happy and excited to see how it looks in 2-3 weeks.
Much is not there in the vial and down pretty much air (something is supposedly always on technical grounds, but it annoys me and that gives wrinkle ;-)
However with me enough 2 thrusts from the donor possibly even one. I hope so in the long fertility.