My 11 year old male was suffering more and more often to joint problems; especially at the ankles. For half a year he gets LUPOSAN as an additive; I remain somewhat below the amount recommended. Improvement was noticeable after the first few weeks; now he is pain-free for weeks. Obviously, it works well and prevents the Verscheiß ago. Existing arthrosis and arthritis is thus probably not be cured, but the dog is gaining painless time.