I have very sensitive skin, which redden easily, dryness, tightness and itchiness. From my dermatologist I got this one up mixed cream from the pharmacy. Disadvantage: Always go to the doctor for prescription cream limited period preserved. With the sensitive day and night care of Nivea I get by just as well and it is cheaper than the prescription fee. Unfortunately, she was genommenm in our DM from the program, so I order now.