Without exception, all F-keys can be used (F1-F12) also as normal function keys, easy to install Logitech Setpoint and switch to the good old F-key functionality with one click everything - costs less than 5 minutes. After the initial conversion, there is not a single function key more (F1-F12) which must be called by FN-FX.
CTRL-ALT-F4 is and remains thus CTRL-ALT-F4
I write the way grade with this keyboard - it is very good for my taste, the conversion took less than 2 minutes, given the price-performance ratio excellent office work machine.