The effect of the drug itself, I would describe times as good to very good. Also that the Pen only apply once a week should I find super - that is the positive thing about this product, for the three stars. What is not so great: The pin indicates the pen tip no active ingredient from there it is completely dry, despite the correct storage and handling (tested on paper, where you can easily see whether liquid is present). At the pin edge (ie at the sides of the pen tip), however, we made the drug very well. The dry peak however, makes it impossible to apply the product in small areas and pinpoint accuracy, so you either held vertically pin no means brings to the skin, or - in heavily tilted pen - an incorrect or wets a much too large an area and healthy skin harms. The pen is not superimposed, was purchased new and only 3-4 times used (ie can not possibly be empty). He was lying not left open or the like, which may promote dehydration. Service life by purchasing approximately 2.5 years (until 04/2016). Therefore I do not assume that it could be a layered product package, but a fundamental problem with this article. Would grab the next time probably to a conventional liquid back, even if not quite as easy and convenient to use.