The first impression is the comfort provided by the ergonomics: natural position of the forearm to the handling of the mouse. Its use requires a period of adaptation to properly manipulate buttons "left" (verical top) and "right" (vertical center) without accidentally pressing other buttons (thumb button down and vertical). Ease of use, however, at the expense of precision and cursor stability (double-click without moving the cursor is not easy!). Another difficulty compared to a mouse "standard" => lift the mouse to reposition it requires placing the thumb at the base of the mouse. In summary: very well for the "human" ergonomics, less for the ergonomics of use.
Note: the software included on the mini CD does not configure all the mouse buttons. You must download the latest version on the site of Evoluent.