MSM is a super middleweight. I use it to painful inflammation associated with severe hip osteoarthritis, which results partly as severe pain that I often take painkillers and often can not sleep because of pain. All this now belongs to the past. Since I take MSM, now for about a week, the pain subsides continuously, so that I now - after this first short administration time - no painkillers or anti-inflammatory drugs have to take more. This is a real benefit. The capsules can be taking well. However, I take significantly more than indicated on the package. Due to information I've read that in severe inflammation and more MSM is needed, I took at first for 3 days, the recommended dose of 3 capsules a day, gradually raise currently I use 5 x 2 capsules, which are therefore 5 g MSM. It should be mentioned that I had diarrhea and headache light after a few days, but on these phenomena has been variously stated in the Internet, however, the side effects disappear quickly when the body has continued to become accustomed to the substance. Now I have no more side effects, only the super formula against the terrible arthritis inflammation pain, I feel like neugeborgen and can again walk longer distances without pain. I would like to recommend additionally the intake of collagen hydrolyzate, for. Example, also here at Amazon by Manako or gelatin Gold Extra St. Bernhard Kräuterhaus. I suspect that the combination of collagen hydrolyzate achieved with MSM capsules with me the excellent effect. THANK YOU VERY MUCH perform far less harm to these great dietary supplement that much better help than expensive drugs and the body. Absolute buy recommendation.