I took me this product to clean my gut and on the recommendation from the center of health here at Amazon. For this I got myself psyllium husks and Bentoitpulver to the morning to make me a shake for intestinal cleansing. Combi Flora I took 2x daily, morning and evening. The first day went well, on day 3 and 4 I had apparently also a euphoria thrust and felt just great. From day 6 circa we went but steadily down and I noticed how I slowly got a depression again. And such I had not had for several months. A similar phenomenon I experienced even with the probiotic "Primal Defense". Because I felt even limp, depressed and I felt dizzy even after a few days. Anyway, this announcement was a sign of depression settle this product. I am aware that there may be an aggravation for some products, but a depression I do not count it. This can possibly slight fatigue or headaches be, but from depressive thoughts. After 2 days without the probiotic, it went back much! So stay away from this product people do not buy recommendation!