I have since my childhood regularly herpes and had always tried to tackle with creams or patches against it. That worked more or less well - saw in the case of creams always stupid (you've got what at the lip ....). At first I was very skeptical, but that part could try. I can only say - never again no. It is somewhat difficult to endure the heat for very sensitive people, but does affect the pen very well. If it itches somewhere just keep discreet pin to the location and press the button. This is due to the heat is not always fun, but usually the bubbles then do not come with me, or very weak. I'm glad to be able to use this part and so much to have fewer problems with my Herpes!