I had a mouse of a rather unknown manufacturer with 2 thumb buttons before this mouse. I found this was already a major improvement in my game feeling. So I was looking for a mouse but not too many more thumb buttons. The Razer Hex gives me just that. Good ergonomics (have rather small hands) precise control, useful for the blind operation suitable thumb buttons. I am MMO casual gamers (Lord of the Rings Online, SWTOR, Guild Wars 2) and find just for Reactive skills is a significant gain.
Only the software I do not consider optimal, but is a question of taste I think