About all the benefits almost everything has already been said. However, I would add one more thing. One can virtually unlimited number of devices using the remote control, not only the 4. specified Anyone with a little time and with the old remote control simply takes on the individual commands in the new manual will save so a lot of money. So for me, the commands are stored, for example of my video player to the TV set. Since I only need a button to turn on the TV, the other buttons would otherwise unoccupied. Even devices with just a few commands are controllable. Who uses as radio outlets, can also control these have their own keys. So you will save with this feature ultimately 200% compared to the more expensive Harmony 600 controllable with 5 devices.
After a year tired the first keys. The CH + and CH- buttons to be used only with a lot of pressure. Then I turned to the Logitech customer service. After I got over the technical hurdles the Logitech service (not reply by e-mail at service-mails, but logged by Logitech Homepage reply!), I was sent to a Brand New. The key assignment from the old remote control can easily be taken over by the software. The old I could keep, but I can not reprogram it using software. The device number is not available.