I own a Shi Tzu bitch 1year old and use the spot now for 3 times. They tolerate it without any problems, not even the smell bothers you otherwise would wallow around on his back, trying to mask the odor. Ticks they had since then only one, namely, 2 days after the 1st treatment, the worst time ticks in spring but also was nearly over when I used the middle. I later found still ticks in fur, but deadlocked since then has no longer. At the moment I try to treat the mites. Basically each spot should made whether synthetically or biologically, are carefully tested on animals, ie use only one point with a drop, then wait and see because doing reactions also may occur only after several days. Of course, this contradicts the stated use of the products, where they initially gladly frequent and generous use the funds. Also, I do not believe such means constantly or einzusetzten too often. Approximately 1-2 months in the worst time ticks, which I also only once every 2 weeks behalf 2-3 drops and otherwise, I use it only in case of infestation. An error will gladly committed, the means should be as. To the places that can not lick the animal or even otherwise when cleaning not licking like the neck or chest area