"EUGENOL is cytotoxic [12] and genotoxic, and the genotoxic effects are dependent on activation by the enzyme cytochrome P450 [13] It is both an antioxidant and a prooxidant,. Based on the latter probably his (mucus) skin-irritating, allergy-promoting effect [. 14] "
LIME:.. "In the metabolism of limonene mainly arises Perillinsäure, Dihydroperillinsäure, limonene-1,2-diol and Uroterpenol Limonene is irritating its oxidation products D - () - carvone and more isomers of limonene oxide, arising from limonene in the air, allergenic. [14]