Alice, fifties, is Professor at Harvard in Boston cognitive psychology. She researcher husband, like her, and three children. Everything will start with a lack of the word (the word "lexicon") at a conference. Then one day she is lost in her neighborhood. She finally make an appointment with their GP and a neurologist. After eliminating various assumptions, was diagnosed with early Alzheimer's. Then the slow descent into memory loss: short-term losses, confusion ... and quickly disorders are increasing. It ends up no longer recognize her husband, her daughters herself. A novel in which we live "inside" the progressive loss of memory. The experience of an Alzheimer's patient is simulated in a nice romantic frame. Despite the tragedy of history, there is no lamentation. Sad indeed, but informative about the disease.