Except for the ISO button I can reach all the buttons well with wrist strap. Therefore, I have put in the advanced settings the ISO button on the SET button, and already I have no more problems.
At first I had attached the wrist strap still without battery grip on my 550D and with the wheel below the tripod socket. Because this attachment also once a thread has down, you can still attach a tripod or a quick release plate on it. Really stable but that is not then. Firstly, the overall connection is shaky and the other often dissolves the loop holder instead of the tripod plate while trying to solve the latter. The tripod plate off let's also not optimal, since the plate thanks to the lower Supporting table not so stuck on the loop fastener, such as directly on the camera. So if you often his camera mounted on a tripod, thus is not happy and I strongly advise a battery grip as the battery grip for Canon EOS 550D and 600D - like BG-E8. Thus, the tripod thread is then free again and the battery grip has many other benefits (see reviews there).
Ultimately, is now still the troublesome strap in the way, which one needs but every now and then to have your hands free. Here I highly recommend this wegzumachen to contact the ton, belongs and go up a strap as the Phorex anti-slip Universal Camera Strap / strap where he. The Tragegefuehl improves significantly and you can quickly solve the belt so that one only holds the camera with the strap in his hand.
I can not live without wrist strap and eventually I actually bought the battery grip only for the sake of this wrist strap today. The combination makes it ;-)