I use the Intuos 4 Wireless also much with Lightroom. Here the use is significantly impaired, but also useful. Especially when Adjustment Brush makes Tabelt sense since you can work much more accurate and pressure sensitive here too. Especially for very fine changes I do not like the Wacom miss.
Wireless is a nice luxury, the Intuos cable does the same. But in some situations, I do not miss the wireless tablet. Wants to work on her lap example in workshops or if you just want time to sit back at the desk and the tablet.