I use it when I have to leave a few days, Of course I will not abandon them because there is someone who take care of them during my absence. But cats sometimes have funny ways to make us see their discontent. For more surprises on the way ... My cats are quiet and ZEN! At the most it takes me 3 refills per year .. But for those to use it permanently it will take 1 refill per month .. Best of all will you money compared to prices practiced at the pharmacy or at the vet